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Bhasin-Shalender

Shalender Bhasin, MD
Brigham and Women’s Hospital
Harvard Medical School

  • Principal Investigator and Director, Boston Claude D. Pepper Older Americans Independence Center
  • Professor of Medicine, Harvard Medical School
  • Director, Research Program in Men’s Health: Aging and Metabolism, BWH

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Dr. Bhasin is an internationally recognized expert in human aging, clinical trials of function promoting therapies for older adults, functional decline in aging, and testosterone biology. He chaired the Endocrine Society’s Expert Panel for the development of Guidelines for Testosterone Therapy. He is a translational researcher, with over 250 peer-reviewed manuscripts, 130 reviews and book chapters. Dr. Bhasin’s research has led to new applications of androgens and selective androgen receptor modulators. His pioneering research in androgen biology and anabolic therapies for aging-associated sarcopenia has been supported by several NIH-funded grants.

He received his MD from the All India Institute of Medical Sciences in New Delhi, India, residency training at Northwestern University Medical School and fellowship training in Endocrinology and Nutrition at Harbor-UCLA Medical Center in Los Angeles, CA.

Dr. Bhasin has been the recipient of numerous teaching and research awards. He has served as: Associate Editor of the JCEM; Chair of the Clinical Guidelines Committee of the Endocrine Society; Chair of the Clinical Guidelines Panel of the Endocrine Society for diagnosis and treatment of hypogonadism; and Chair of American Board of Internal Medicine Endocrinology and Metabolism Board. He has been selected as one of the Best Doctors in America by Castle Connolly and by Boston Magazine. He is the recipient of the 2015 Outstanding Clinical Investigator Award of the Endocrine Society.

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Monty Montano, PhD
Brigham and Women’s Hospital
Harvard Medical School

  • Principal Investigator
  • Scientific Director, Boston Claude D. Pepper Older Americans Independence Center

Monty Montano PhD is a Principal Investigator at Harvard Medical School and the Director of Muscle and Aging Interventions at Brigham and Women’s Hospital. Dr. Montano received a Ph.D. in Genetics from Stanford University School of Medicine and did his postdoctoral work at the Harvard School of Public Health. He conducts international translational research on aging, musculoskeletal regeneration, and chronic HIV infection. Dr. Montano is the principal investigator of an NIH-sponsored 5-year study to comprehensively evaluate physical function and muscle maintenance in older individuals with HIV infection on effective therapy compared to age-matched uninfected individuals.  Dr. Montano is a chartered member of the National Institutes of Health Center for Scientific Review and he is the author of a book on translational medicine entitled, “Translational Biology in Medicine: Models from Aging, Muscle Regeneration and Infection.”

Representative Papers

Atypical Skeletal Muscle Profiles in HIV+ Asymptomatic Middle-Aged Adults.
Biomarker signatures of aging.
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1.
Premature expression of a muscle fibrosis axis in chronic HIV infection.
Age and Sex Distributions of Age-Related Biomarker Values in Healthy Older Adults from the Long Life Family Study.

RogerFielding

Roger Fielding, PhD
Tufts University School of Medicine

  • Associate Director, Boston Claude D. Pepper Older Americans Independence Center
  • Professor of Medicine, Tufts University School of Medicine
  • Professor of Nutrition, Tufts University Friedman School of Nutrition Science and Policy
  • Lab Director and Senior Scientist of the Nutrition, Exercise Physiology, and Sarcopenia (NEPS) Laboratory

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Dr. Fielding is an internationally known researcher who studies the underlying mechanisms contributing to the age-associated decline in skeletal muscle mass, the resultant impact on function, and the potential role of exercise and physical activity on attenuating this process. Dr. Fielding has a strong record of NIH funding and oversaw the development of the interventions for the LIFE (Lifestyle Interventions for Elders) Pilot study and served as the Chair of the LIFE Intervention and Operations Committee. He also is a co-investigator and chair of the Body Composition Analysis committee for the NIA-funded “Calerie” trial.

Lipsitz Lewis A

Lewis A. Lipsitz, MD
Beth Israel Deaconess Medical Center
Hebrew SeniorLife
Harvard Medical School

  • Associate Director, Claude D. Pepper Older Americans Independence Center
  • Chief of Gerontology, Beth Israel Deaconess Medical Center
  • Professor of Medicine, Harvard Medical School
  • Director and Senior Scientist, Hinda and Arthur Marcus Institute for Aging Research
  • Vice President for Academic Medicine, Hebrew SeniorLife

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Dr. Lipsitz was one of the first geriatricians to be trained in the Harvard Geriatric Fellowship Program. He subsequently became a National Institute on Aging Academic (K23) Awardee, with Hebrew SeniorLife (formerly the Hebrew Rehabilitation Center for Aged) as his primary clinical and research site. As a fellow, he began a systematic series of epidemiologic and physiologic studies evaluating syncope and abnormal blood pressure regulation, discovered postprandial hypotension in the elderly, and subsequently acquired funding for his studies through an NIA-funded Program Project, which he directed for 20 years. In this capacity he provided on-site management and established strong working relationships with project directors from multiple Harvard-affiliated institutions. This program project supported the prospective, observational MOBILIZE Boston Study, which has elucidated numerous novel risk factors for falls over the past 10 years. Dr. Lipsitz’s research has been quite productive, resulting in 250 original articles in peer-reviewed journals, many of which involve clinical trials and translational research.

During his career, Dr. Lipsitz has received continuous NIA funding for his research, directed an Older Americans Independence Center, led a T32 training program and the Hartford Center of Excellence in Geriatric Medicine at Harvard Medical School (HMS), and acquired two D.W. Reynolds Grants for geriatric education at HMS. He has mentored 34 successful postdoctoral trainees, including 2 Beeson Scholars and 4 T32 trainees, and received the prestigious “William Silen Lifetime Achievement” award for mentoring. His research into various function promoting therapies, access to Harvard-wide resources, academic leadership experience, skills in mentoring, and familiarity with NIA Center Grants and Boston’s academic geriatric community all make him ideally suited to lead the Boston OAIC and its Research Education Component.

Jette Alan

Alan M. Jette, PhD, MPH, PT, FAPTA
Boston University School of Public Health
MGH Institute of Health Professions 

  • Professor of Health Policy & Management, Boston University School of Public Health
  • Director, Health & Disability Research Institute, Boston University School of Public Health
  • Professor, Center for Interpersonal Studies and Innovation, MGH Institute of Health Professions

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Dr. Jette’s is an internationally recognized expert in the measurement of function and disability.  He has developed numerous instruments that assess function and disability and has published numerous articles on these topics in the rehabilitation, geriatrics, and public health literature.  Dr. Jette’s current research interests include the measurement, epidemiology, and prevention of disability, and the development and dissemination of contemporary outcome measurement instruments to evaluate the quality of health care.

Edward Marcantonio, MD
Beth Israel Deaconess Medical Center
Harvard Medical School

  • Section Chief for Research in the Division of General Medicine and Primary Care, BIDMC
  • Professor of Medicine, Harvard Medical School

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Dr. Marcantonio’s is an internationally recognized expert and clinical investigator in the area of delirium. He has conducted a series of observational and interventional studies designed to improve delirium identification, target individuals at risk, identify modifiable risk factors, and test intervention strategies to reduce the incidence, severity and duration of delirium. He currently lead three NIH-funded studies in delirium research, including the Biomarker Discovery for Delirium project within the first NIH-funded program project in the field of delirium research.

Kiel Douglas

Douglas P. Kiel, MD, MPH
Marcus Institute for Aging Research
Hebrew SeniorLife
Harvard Medical School

  • Professor of Medicine, Harvard Medical School
  • Director, Musculoskeletal Research Center, Hebrew SeniorLife
  • Associate Member, Broad Institute of Harvard and MIT

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Dr. Kiel’s research focuses on the epidemiology of osteoporosis and related fractures, including lifestyle factors, biomarkers, and genetic factors.  He is also interested in sarcopenia and its consequences, including falls and disability.  He also has conducted multiple clinical trials targeting the musculoskeletal system.  He leads the Framingham Osteoporosis Study, and serves in leadership roles for many organizations including the NIH, American Society for Bone and Mineral Research, National Osteoporosis Foundation, and the Joint Commission.

Wagers Amy

Amy Wagers, PhD
Joslin Diabetes Center
Harvard Stem Cell Institute

Harvard University

  • Co-chair, Harvard Department of Stem Cell and Regenerative Biology
  • Forst Family Professor of Stem Cell and Regenerative Biology, Harvard University
  • Principal Faculty, Harvard Stem Cell Institute
  • Senior Investigator, Islet Cell and Regenerative Biology, Joslin Diabetes Center
  • Co-Director DERC/HSCI Flow Cytometry Core, Josilin Diabetes Center

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Dr. Wagers is an established investigator who has led a research laboratory studying the regenerative biology of aging for more than 10 years. She is also a Principal Faculty member of the Harvard Stem Cell Institute and serves on its Executive Committee. Dr. Wagers is a recipient of the Burroughs Wellcome Fund Career Award, the Beckman Foundation Young Investigator Award, the WM Keck Foundation Distinguished Young Scholar Award, and the NIH Director’s New Innovator Award. Her current research focuses on defining the factors and mechanisms that regulate the migration, expansion, and regenerative potential of adult blood-forming and muscle-forming stem cells.

She received her Ph.D. in Immunology and Microbial Pathogenesis from Northwestern University in 1999, and then worked as a postdoctoral fellow studying stem cell biology in the laboratory of Dr. Irving Weissman in the Department of Pathology at Stanford University School of Medicine.

Thomas Travison, PhD
Marcus Institute for Aging Research
Hebrew SeniorLife
Harvard Medical School

  • Director of Biostatistics, Marcus Institute for Aging Research, Hebrew SeniorLife
  • Co-Director of the Interventional Studies in Aging Center
  • Senior Scientist, Marcus Institute for Aging Research
  • Associate Professor of Medicine, Harvard Medical School

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Thomas Travison is Senior Scientist and Director of Biostatistics at the Hebrew SeniorLife Institute for Aging Research (IFAR), Associate Professor of Medicine at Harvard Medical School. He co-directs the Interventional Studies in Aging Center at IFAR. Dr. Travison’s work has focused on the interface between the endocrinology of aging and functional decline, on multicomponent interventions for the prevention of loss of independence in aging, and on graphical data display. He was lead author on the development of the first assessments of clinical significance of androgen supplementation for improvement of physical function in frail men with mobility limitation, and of the durability of androgen insufficiency in community-dwelling men. He is lead biostatistician on the NIA / FNIH Sarcopenia Consortium, which addresses the influence of body mass and function on mobility limitation and downstream clinical endpoints. He leads the analytic team for the Endocrine Society / CDC / PATH multicohort derivation of age-specific sex steroid reference ranges in men, and has designed and analyzed numerous clinical trials of function-promoting interventions in older women and men. 

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Ravi Jasuja, PhD
Brigham and Women’s Hospital
Harvard Medical School

  • Director, Translational Research and Discovery, Men’s Health: Muscle and Metabolism, BWH
  • Lecturer on Medicine, Harvard Medical School

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Small Animal Resource Core Leader Ravi Jasuja received his Bachelor’s degree in Technology from the Indian institute of Technology, Delhi , PhD from the University of Hawaii, Manoa with Dr. Randy Larsen and conducted his postdoctoral research with Dr. Shahid Khan (at Albert Einstein College  of Medicine)  and Dr. Frank Ferrone (at Drexel University). Dr. Jasuja is an Assistant Professor of Medicine in the Endocrinology section and the director of Metabolic Phenotyping Core. His research interests include: 1. Biophysical characterization of ligand-specific conformational dynamics in Androgen Receptor 2. Mechanisms of tissue-specific action of androgens on muscle, bone, prostate adipose tissue remodeling by circulating androgens in animal models and development of Selective Androgen Receptor Modulators.

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Nancy Latham, PhD, PT
Brigham and Women’s Hospital
Harvard Medical School

  • Associate Epidemiologist, Brigham and Women’s Hospital
  • Lecturer on Medicine, Harvard Medical School

Nancy Latham, PhD, PT is an Associate Epidemiologist at Brigham and Women’s Hospital and a Lecturer in the Department of Medicine at Harvard University in Boston Massachusetts.  She completed her training in Physical Therapy at the University of Toronto and McGill University, a PhD at the Clinical Trials Research Unit at the University of Auckland and a NIDRR post-doctoral fellowship in Health Services Research at Boston University. Her research interest is in applying methods from the field of clinical epidemiology, such as randomized controlled trials, cohort studies and meta-analyses, to rehabilitation and disability-related research. She is particularly interested in innovative interventions to extend the benefits of rehabilitation programs to people in the community after usual rehabilitation care ends. She was a co-principal investigator of the HIP Rehab trial, an RCT of a home-based exercise program for people after hip fracture which was published in JAMA. She is currently the Study Director of the STRIDE study, a pragmatic randomized controlled trial of a primary care based intervention to reduce serious fall-related injuries in 10 health systems in the U.S.A.  She is also the PI on studies to evaluate technology to improve health and function in persons with Parkinson Disease and Spinal Cord Injury. She is a Fellow of the Gerontological Society of America and is on the editorial board of Archives of Physical Medicine and Rehabilitation.